Principles in Patterns (PiP) : Institutional Approaches to Curriculum Design Institutional Story

The principal outputs of the PiP Project surround the Course and Class Approval (C-CAP) system. This web-based system built on Microsoft SharePoint addresses and resolves many of the issues identified by the project. Generally well received by both academic and support staff, the system provides personalised views, adaptive forms and contextualised support for all phases of the approval process. Although the system deliberately encapsulates and facilitates existing approval processes thus achieving buy-in, it is already achieving significant improvements over the previous processes, not only in reducing the administrative overheads but also in supporting curriculum design and academic quality. The system is now embedded across three faculties and is now considered by the University of Strathclyde to be a "core institutional service". Alongside the C-CAP system the PiP Project also cultivated a suite of approaches: an incremental systems development methodology; a structured and replicable evaluation approach, and; Strathclyde's Lean Approach to Efficiencies in Education Kit (SLEEK) business process improvement methodology Each is based on recognised formal techniques, providing the basis for a rigorous approach. This is contextualised within and adapted to the HE institutional context thus building the foundation not only for the project but ultimately for institution wide process improvement. This "institutional story" report summarises the principal outcomes of the Project

Occurrences of \u3ci\u3eEumorpha Fasciata, Hyles Gallii, Sphinx Franckii\u3c/i\u3e and \u3ci\u3eS. Vashti\u3c/i\u3e (Lepidoptera: Sphingidae) in Illinois

A recent survey of private and institutional collections in Illinois and surrounding states has provided specific information on the occurrences of four species of sphingids within Illinois: Eumorpha fasciata, Hyles gallii, Sphinx franckii, and S. vashti. Geographical and phenological data for these species are provided

A Traffic Survey of the City of Sioux Falls, South Dakota

How to control the traffic on the streets of our cities is becoming one of the most important problems of the present day. an urban community depends for its existence upon the transportation facilities both internal and external. The external transportation is necessary for a city\u27s growth because food supplies and raw materials must be brought into the city and the commodities which are produced in the cities must be distributed to other places

A Study to Determine the Impact of Instructional Technology on Hampton Roads Area Teachers in the Development of Classroom Instruction

This study sought to answer the following questions: 1. Do teachers currently use instructional technology in the classroom? 2. Doe teachers consider using available instructional technology during course and lesson planning? 3. Do teachers feel confident enough to use instructional technology in the classroom

Institutional Approaches to Curriculum Design Institutional Story : [Principles in Patterns Project - PiP]

The principal outputs of the PiP Project surround the Course and Class Approval (C-CAP) system. This web-based system built on Microsoft SharePoint addresses and resolves many of the issues identified by the project. Generally well received by both academic and support staff, the system provides personalised views, adaptive forms and contextualised support for all phases of the approval process. Although the system deliberately encapsulates and facilitates existing approval processes thus achieving buy-in, it is already achieving significant improvements over the previous processes, not only in reducing the administrative overheads but also in supporting curriculum design and academic quality. The system is now embedded across three faculties and is now considered by the University of Strathclyde to be a "core institutional service". Alongside the C-CAP system the PiP Project also cultivated a suite of approaches: an incremental systems development methodology, a structured and replicable evaluation approach, and Strathclyde's Lean Approach to Efficiencies in Education Kit (SLEEK) business process improvement methodology Each is based on recognised formal techniques, providing the basis for a rigorous approach. This is contextualised within and adapted to the HE institutional context thus building the foundation not only for the project but ultimately for institution wide process improvement

LOW-RANK COAL: Its Present and Future Role in the United States

Low-rank coals-lignite and subbituminous coal-are those that have been subjected to the least metamorphic change during the coal-forming process. As such, they retain greater fractions of moisture and volatile matter and contain less fixed carbon than the high-rank coals-bituminous and anthracite. The primary measure used to classify the lower ranks of coal is the heating value. Lignite is defined by the American Society for Testing and Materials (standard D-388) as coal with a heating value less than 8300 Btujlb, on a moist, mineral-matter-free basis (m,mmf). Subbituminous coal ranges in heating value from 8300 to 11,500 Btujlb (m,mmf). Bituminous coal and anthracite range from 10,500 to over 15,000 Btu/lb (m,mmf)

Public Affairs are Your Affairs

Throughout American history, the trend has been toward giving more and more people the right to vote. But the people seemingly have become less and less interested in voting. Our country has increased in size. Our government and pattern of life have become more complex

The adoption of two farm practices in a central Iowa community

One of the salient characteristics of modern American agriculture is its rapidly changing technology. New practices and techniques are constantly being developed by research agencies. Society benefits from these research findings, however, only to the degree that they are diffused to and used by farmers.https://lib.dr.iastate.edu/specialreports/1023/thumbnail.jp

The Second-Shell Metal Ligands of Human Arginase Affect Coordination of the Nucleophile and Substrate†

ABSTRACT: The active sites of eukaryotic arginase enzymes are strictly conserved, especially the first- and second-shell ligands that coordinate the two divalent metal cations that generate a hydroxide molecule for nucleophilic attack on the guanidinium carbon of L-arginine and the subsequent production of urea and L-ornithine. Here by using comprehensive pairwise saturation mutagenesis of the first- and second-shell metal ligands in human arginase I, we demonstrate that several metal binding ligands are actually quite tolerant to amino acid substitutions. Of>2800 double mutants of first- and second-shell residues analyzed, we found more than 80 unique amino acid substitutions, of which four were in first-shell residues. Remarkably, certain second-shell mutations could modulate the binding of both the nucleophilic water/hydroxide molecule and substrate or product ligands, resulting in activity greater than that of the wild-type enzyme. The data presented here constitute the first comprehensive saturation mutagenesis analysis of a metallohydrolase active site and reveal that the strict conservation of the second-shell metal binding residues in eukaryotic arginases does not reflect kinetic optimization of the enzyme during the course of evolution. Arginases (EC 3.5.3.1) are typically homotrimeric enzymes with an R/β fold comprising an eight-strand β-sheet surrounded by several helices. The enzyme contains a dinuclear metal center tha